6 Results for "

IEM

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "IEM" in MCE Product Catalog:

Cat. No.: HY-103230
CAS No.: 121034-89-7
Purity:  ≥98.0%
Target:  

iGluR

Research Areas:  

Neurological Disease

IEM-1460 blocks both AMPA and NMDA glutamate receptor with anticonvulsant effect in vivo .
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Cat. No.: HY-100547
CAS No.: 162831-31-4
Purity:  98.03%
Target:  

iGluR

Research Areas:  

Neurological Disease

IEM-1754, a dicationic adamantane derivative, is a potent blocker of open channels of native ionotropic glutamate receptors including quisqualate-sensitive receptors in insect muscles, NMDAR in cultured rat cortical neurons, and AMPAR in freshly isolated hippocampal cells. IEM-1754 shows anticonvulsant potency in vivo .
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Cat. No.: HY-103232
CAS No.: 258282-23-4
Target:  

mGluR

Research Areas:  

Neurological Disease

IEM-1925 bromide is an orally active glutamate receptor antagonist, increases the latent period and decreases the duration of status epilepticus in rats in a lithium-pilocarpine model of epilepsy .
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Cat. No.: HY-169421
Target:  

Sodium Channel

Research Areas:  

Cancer

Nav1.7-IN-18 (Compound 31) is a Nav1.7 inhibitor with a Ki value of 4.9 nM and an IC50 of 13 nM, showing analgesic effects in transgenic mice with inherited erythromelalgia (IEM) .
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Cat. No.: HY-103230R
CAS No.: 121034-89-7
Research Areas:  

Neurological Disease

IEM-1460 (Standard) is the analytical standard of IEM-1460 (HY-103230). This product is intended for research and analytical applications. IEM-1460 blocks both AMPA and NMDA glutamate receptor with anticonvulsant effect in vivo .
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Cat. No.: HY-W274652
CAS No.: 5555-22-6
Synonyms: IEM-1770
Target:  

iGluR Drug Derivative

Research Areas:  

Neurological Disease

Benzylaspartic acid (IEM-1770), a derivative of aspartic acid, is a NMDA agonist. Benzylaspartic acid has antidepressant activity. Benzylaspartic acid blocks alcohol-abstinence syndrome (AAS) development in chronic alcohol drinking rat models. Benzylaspartic acid can be used for depression research .
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