258282-23-4
258282-23-4
Chemical Structure
IEM-1925 bromide
- CAS No.: 258282-23-4
- Formula:C17H30Br2N2
- Molecular Weight:422.24
IUPAC Name: N1-(1-phenylcyclohexyl)pentane-1,5-diamine dihydrobromide
InChIKey: ZCYUSVRXEKAQSL-UHFFFAOYSA-N
SMILES: NCCCCCNC1(C2=CC=CC=C2)CCCCC1.Br.Br
Biological Activity:
IEM-1925 bromide is an orally active glutamate receptor antagonist, increases the latent period and decreases the duration of status epilepticus in rats in a lithium-pilocarpine model of epilepsy[1][2].
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IEM-1925 bromide | 98.0% | IEM-1925 bromide is an orally active glutamate receptor antagonist, increases the latent period and decreases the duration of status epilepticus in rats in a lithium-pilocarpine model of epilepsy. |
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References
- [1]. D B Tikhonov, et al. Voltage-dependent block of native AMPA receptor channels by dicationic compounds. Br J Pharmacol. 2000 Jan;129(2):265-74. [Content Brief]
- [2]. S. I. Vataev, et al. IEM-1925, a Glutamate Receptor Channel Blocker, Increases the Latent Period and Decreases the Duration of Status Epilepticus in Rats in a Lithium-Pilocarpine Model of Epilepsy. Neuroscience and Behavioral Physiology volume 51, pages976–984 (2021).
Keywords
