5555-22-6
5555-22-6
Chemical Structure
Benzylaspartic acid
Synonym(s): IEM-1770
- CAS No.: 5555-22-6
- Formula:C11H13NO4
- Molecular Weight:223.23
IUPAC Name: benzylaspartic acid
InChIKey: RKSKSWSMXZYPFW-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)CNC(CC(=O)O)C(=O)O
Biological Activity: Benzylaspartic acid (IEM-1770), a derivative of aspartic acid, is a NMDA agonist. Benzylaspartic acid has antidepressant activity. Benzylaspartic acid blocks alcohol-abstinence syndrome (AAS) development in chronic alcohol drinking rat models. Benzylaspartic acid can be used for depression research[1][2].
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Benzylaspartic acid | Benzylaspartic acid (IEM-1770), a derivative of aspartic acid, is a NMDA agonist. Benzylaspartic acid has antidepressant activity. Benzylaspartic acid blocks alcohol-abstinence syndrome (AAS) development in chronic alcohol drinking rat models. Benzylaspartic acid can be used for depression research. | |||||||||||||||||||||
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References
- [1]. Schlösser R, et al. Altered benzodiazepine receptor sensitivity in alcoholism: A study with fMRI and acute lorazepam challenge[J]. European Neuropsychopharmacology, 2002, 12: 397-398.
- [2]. Petrov VI, et al. Antidepressant activity of aspartic acid derivatives. Bull Exp Biol Med. 2001 Apr;131(4):342-5. [Content Brief]
Keywords
