1 Result for "

IS4

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "IS4" in MCE Product Catalog:

Cat. No.: HY-P11019
CAS No.: 3067986-23-3
Target:  

CXCR Calcium Channel

Research Areas:  

Cancer

IS4 is a selective CXCR4 competitive antagonist, with an IC50 of 0.65 nM in THP-1 cells and 38.75 nM in Jurkat cells. IS4 is stable in serum and non-cytotoxic. IS4 competitively binds to CXCR4 with CXCL12, thereby inhibiting CXCL12-induced intracellular Ca 2+ release and cancer cell migration. IS4 can be used in the research on the prevention of metastasis of breast cancer, prostate cancer, leukemia, and other diseases .
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