2 Results for "

ITAM

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "ITAM" in MCE Product Catalog:

3
3 Cited Publications
Art. -Nr.: HY-136179
CAS. Nr.: 873080-25-2
Reinheit:  99.88%
Target:  

Tyrosinase

Forschungsgebiete:  

Inflammation/Immunology

ZAP-180013 is a zeta-chain-associated protein kinase 70 (ZAP-70) inhibitor with an IC50 of 1.8 μM. ZAP-180013 inhibits the interaction of ZAP-70 SH2 domain with immunoreceptor tyrosine-based activation motif (ITAMs) .
Art. -Nr.: HY-P99653
CAS. Nr.: 1929549-92-7
Synonyms: VAY-736

Target:  

TNF Receptor

Forschungsgebiete:  

Cancer

Ianalumab (VAY-736) is a human, decarboxylated antibody against BAFF-R. Ianalumab can block the interaction between BAFF and BAFF-R and antagonize the apoptosis protection mediated by BAFF. Ianalumab exerts antibody-dependent cytotoxic (ADCC), depending on effector cell activation mediated by immune receptor tyrosine activation motif (ITAM) .