873080-25-2
873080-25-2
Chemical Structure
ZAP-180013
- CAS No.: 873080-25-2
- Formula:C19H17Cl2N3O4S
- Molecular Weight:454.33
IUPAC Name: 5-chloro-N-(4-chlorobenzyl)-2-(ethylsulfonyl)-N-(furan-2-ylmethyl)pyrimidine-4-carboxamide
InChIKey: GTWKIPDKVRLUKN-UHFFFAOYSA-N
SMILES: O=C(C1=NC(S(=O)(CC)=O)=NC=C1Cl)N(CC2=CC=C(Cl)C=C2)CC3=CC=CO3
Biological Activity: ZAP-180013 is a zeta-chain-associated protein kinase 70 (ZAP-70) inhibitor with an IC50 of 1.8 μM. ZAP-180013 inhibits the interaction of ZAP-70 SH2 domain with immunoreceptor tyrosine-based activation motif (ITAMs)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ZAP-180013 | 99.88% | ZAP-180013 is a zeta-chain-associated protein kinase 70 (ZAP-70) inhibitor with an IC50 of 1.8 μM. ZAP-180013 inhibits the interaction of ZAP-70 SH2 domain with immunoreceptor tyrosine-based activation motif (ITAMs). | ||||||||||||||||||||
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References
Keywords
