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Ianalumab

(Synonyms: VAY-736)
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Based on 1 Customer Validation

Ianalumab (VAY-736) is a human, decarboxylated antibody against BAFF-R. Ianalumab can block the interaction between BAFF and BAFF-R and antagonize the apoptosis protection mediated by BAFF. Ianalumab exerts antibody-dependent cytotoxic (ADCC), depending on effector cell activation mediated by immune receptor tyrosine activation motif (ITAM).

For research use only. We do not sell to patients.

  • Purity : 99.97%
  • CAS No.: 1929549-92-7
  • Molecular Weight:146.44 kDa
  • Storage:
    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Ianalumab
  • Experimental Validation Results for Ianalumab
  • Experimental Validation Results for Ianalumab
  • Ianalumab Chemical Structure
    Ianalumab Chemical Structure
CAS No.: 1929549-92-7
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Top Publications Citing

Use of MCE Products

All TNF Receptor Isoforms

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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized Human BAFFR / TNFRSF13C, Fc Tag can bind Ianalumab. The EC50 for this effect is 10.75 ng/mL.

  • 1/16

    Flow Cytometry analysis of Raji cells labelling TNFRSF13C/BAFFR/CD268 (red) with Ianalumab (anti-TNFRSF13C/BAFFR/CD268) (HY-P99653). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001). Black-Unlabelled control, cells without incubation with primary antibody.

  • Ianalumab Chemical Structure
    1/16
  • Ianalumab
  • Immobilized Human BAFFR / TNFRSF13C, Fc Tag can bind Ianalumab. The EC50 for this effect is 10.75 ng/mL.
  • Flow Cytometry analysis of Raji cells labelling TNFRSF13C/BAFFR/CD268 (red) with Ianalumab (anti-TNFRSF13C/BAFFR/CD268) (HY-P99653). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001). Black-Unlabelled control, cells without incubation with primary antibody.