1 Result for "

JMX0293

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "JMX0293" in MCE Product Catalog:

Cat. No.: HY-144638
CAS No.: 3033232-87-7
Target:  

Apoptosis

Research Areas:  

Cancer

JMX0293 is an O-alkylamino-tethered salicylamide derivative compound. JMX0293 maintains good potency against MDA-MB-231 cell line (IC50 = 3.38 μM) while exhibiting very low toxicity against human non-tumorigenic breast epithelial cell line MCF-10A (IC50> 60 μM). JMX0293 inhibits STAT3 phosphorylation and contribute to apoptosis in TNBC MDA-MB-231 cells. JMX0293 significantly suppresses MDA-MB-231 xenograft tumor growth in vivo without significant toxicity .
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