1 Result for "

JX06

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "JX06" in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-19564
CAS No.: 729-46-4
Target:  

PDHK Apoptosis

Research Areas:  

Cancer

JX06 is a potent, selective and covalent inhibitor of PDK. JX06 inhibits PDK1, PDK2 and PDK3 with IC50s of 49 nM, 101 nM, and 313 nM, respectively. JX06 inhibits PDK1 activity via covalently binding to a cysteine residue in an irreversible manner. JX06 shows significant antitumor activity .
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