729-46-4
729-46-4
Chemical Structure
JX06
- CAS No.: 729-46-4
- Formula:C10H16N2O2S4
- Molecular Weight:324.51
IUPAC Name: morpholine-4-carbothioic dithioperoxyanhydride
InChIKey: KKVYOWPPMNSLCP-UHFFFAOYSA-N
SMILES: S=C(N1CCOCC1)SSC(N2CCOCC2)=S
Biological Activity: JX06 is a potent, selective and covalent inhibitor of PDK. JX06 inhibits PDK1, PDK2 and PDK3 with IC50s of 49 nM, 101 nM, and 313 nM, respectively. JX06 inhibits PDK1 activity via covalently binding to a cysteine residue in an irreversible manner. JX06 shows significant antitumor activity[1].
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JX06 | 99.78% | JX06 is a potent, selective and covalent inhibitor of PDK. JX06 inhibits PDK1, PDK2 and PDK3 with IC50s of 49 nM, 101 nM, and 313 nM, respectively. JX06 inhibits PDK1 activity via covalently binding to a cysteine residue in an irreversible manner. JX06 shows significant antitumor activity. | ||||||||||||||||||||
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References
Keywords
