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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
KAT6B
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "KAT6B" in MCE Product Catalog:
5
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Research Areas:
PF-9363 (CTx-648) is a first-in-class potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer .
Cat. No.: HY-159957
CAS No.: 2520347-03-7
BAY-184 is a selective and orally active KAT6A and KAT6B inhibitor. BAY-184 inhibits KAT6A/KAT6B activity with an IC50 of 71 nM and 83 nM. respectively BAY-184 inhibits ERα transcriptional activity. BAY-184 inhibits proliferation of diverse breast cancer subtypes, and inhibits tumor growth .
Cat. No.: HY-RS07082
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KAT6B Human Pre-designed siRNA Set A contains three designed siRNAs for KAT6B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS22583
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Kat6b Mouse Pre-designed siRNA Set A contains three designed siRNAs for Kat6b gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS29100
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Kat6b Rat Pre-designed siRNA Set A contains three designed siRNAs for Kat6b gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-162997
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KAT6-IN-3 (compund 10) competitively targets KAT6A and KAT6B .
Cat. No.: HY-183256
CAS No.: 2767642-46-4
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BAY-7728 is an orally active and selective dual inhibitor of KAT6A (IC50: 45 nM)/KAT6B (IC50: 95 nM). BAY-7728 can effectively inhibit tumor growth and regulate the acetylation level of histone H3K23. BAY-7728 can be used for tumor research.
Cat. No.: HY-P704206
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KIAA0383; MORF; MOZ2; MYST4Histone acetyltransferase KAT6B; Histone acetyltransferase MOZ2; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4 (MYST-4); Monocytic leukemia zinc finger protein-related factor
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Cat. No.: HY-182468
CAS No.: 3056105-63-3
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OP-3136 is an orally active, highly selective inhibitor of KAT6A and KAT6B. OP-3136 inhibits the proliferation of prostate cancer, ovarian cancer and non-small cell lung cancer cells that express or overexpress KAT6A. OP-3136 reduces the proliferative capacity of cancer cells and suppresses cell growth in ER + breast cancer cell models with KAT6 overexpression. OP-3136 induces tumor regression and inhibits tumor growth in an ovarian cancer xenograft model in immunodeficient mice. OP-3136 inhibits tumor growth in a non-small cell lung cancer xenograft model in immunodeficient mice. OP-3136 can be used in research related to HR +/HER 2- breast cancer, prostate cancer, ovarian cancer and non-small cell lung cancer (NSCLC) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
