1 Result for "

KRA533

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KRA533" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-138188
CAS No.: 10161-87-2
Purity:  98.73%
Target:  

Ras

Research Areas:  

Cancer

KRA-533 is a potent KRAS agonist. KRA-533 binds to the GTP/GDP binding pocket in the KRAS protein to prevent GTP cleavage, resulting in the accumulation of constitutively active GTP-bound KRAS that triggers both apoptotic and autophagic cell death pathways in cancer cells.
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