10161-87-2

KRA-533 Chemical Structure
10161-87-2

Chemical Structure

KRA-533

  • CAS No.: 10161-87-2
  • Formula:C13H16BrNO3
  • Molecular Weight:314.18

IUPAC Name: 4-(4-(2-bromoacetamido)butyl)benzoic acid

InChIKey: WZQJLTLURXNPQG-UHFFFAOYSA-N

SMILES: O=C(O)C1=CC=C(CCCCNC(CBr)=O)C=C1

Biological Activity: KRA-533 is a potent KRAS agonist. KRA-533 binds to the GTP/GDP binding pocket in the KRAS protein to prevent GTP cleavage, resulting in the accumulation of constitutively active GTP-bound KRAS that triggers both apoptotic and autophagic cell death pathways in cancer cells.

Cat. No. Product Name Purity Description Pricing
HY-138188 		KRA-533 98.73% KRA-533 is a potent KRAS agonist. KRA-533 binds to the GTP/GDP binding pocket in the KRAS protein to prevent GTP cleavage, resulting in the accumulation of constitutively active GTP-bound KRAS that triggers both apoptotic and autophagic cell death pathways in cancer cells.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

Keywords