10161-87-2

KRA-533 Chemical Structure
10161-87-2

Chemical Structure

KRA-533

  • CAS No.: 10161-87-2
  • Formula:C13H16BrNO3
  • Molecular Weight:314.18

IUPAC Name: 4-(4-(2-bromoacetamido)butyl)benzoic acid

InChIKey: WZQJLTLURXNPQG-UHFFFAOYSA-N

SMILES: O=C(O)C1=CC=C(CCCCNC(CBr)=O)C=C1

Biological Activity: KRA-533 is a potent KRAS agonist. KRA-533 binds to the GTP/GDP binding pocket in the KRAS protein to prevent GTP cleavage, resulting in the accumulation of constitutively active GTP-bound KRAS that triggers both apoptotic and autophagic cell death pathways in cancer cells.

Cat. No. Product Name Purity Description Pricing
HY-138188 		KRA-533 98.73% KRA-533 is a potent KRAS agonist. KRA-533 binds to the GTP/GDP binding pocket in the KRAS protein to prevent GTP cleavage, resulting in the accumulation of constitutively active GTP-bound KRAS that triggers both apoptotic and autophagic cell death pathways in cancer cells.
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