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Results for "

KRT80

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-RS07468
    KRT80 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    KRT80 Human Pre-designed siRNA Set A contains three designed siRNAs for KRT80 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    KRT80 Human Pre-designed siRNA Set A
    KRT80 Human Pre-designed siRNA Set A
  • HY-161887
    SMARCA2-IN-8

    		Epigenetic Reader Domain Cancer
    SMARCA2-IN-8 (Compound 13) is an orally active inhibitor for SWI/SNF chromatin remodeling complexe SMARCA2 (also known as Brahma homologue, BRM) and SMARCA4 (also known as Brahma-related gene 1, BRG1) with IC50 of 5 and 6 nM. SMARCA2-IN-8 inhibits the proliferation of SMARCA2 mutated cancer cell SKMEL5 with AAC50 of 5 nM. SMARCA2-IN-8 downregulates the SMARCA2-dependent KRT80 gene expression with AAC50 of 10 nM. SMARCA2-IN-8 exhibits antitumor efficacy and good pharmacokinetic characteristics in mice .
    SMARCA2-IN-8
  • HY-161885
    SMARCA2/4-IN-4

    		SWI/SNF Complex Cancer
    SMARCA2-IN-6 is a SMARCA2 and SMARCA4 inhibitor, with an IC50 value of <0.005 μM for both SMARCA2 and SMARCA4. SMARCA2-IN-6 exerts anticancer activity against BRG1-mutant melanoma. SMARCA2-IN-6 can be used for research related to Brg1/Smarca4-mutant cancers .
    SMARCA2/4-IN-4
  • HY-183939
    L1-CIDE-BRM1-13

    		PROTAC-Linker Conjugates for PAC Others
    L1-CIDE-BRM1-13 (Compound 15) is a linker-drug precursor moiety formed by the covalent conjugation of a PROTAC degrader with a linker for degrader-antibody conjugates (DACs). L1-CIDE-BRM1-13 can be used for the synthesis of DACs .
    L1-CIDE-BRM1-13

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