2760138-46-1
Chemical Structure
L1-CIDE-BRM1-13
- CAS No.: 2760138-46-1
- Formula:C83H104N18O13S
- Molecular Weight:1593.89
InChIKey: ILUOLGZZMLSZRW-VKDZEREYSA-N
SMILES: O=C(C1(C(NCCCCCN2C(C=CC2=O)=O)=O)CCC1)N[C@@H](CCCNC(N)=O)C(NC3=CC=C(COC4=CC=CC=C4C5=CC(N6CC7N(C8=CC(OCCN9[C@H](C)CN(CCOC%10=NOC([C@@H](C(C)C)C(N%11[C@@H](C[C@@H](O)C%11)C(N[C@H](C(C=C%12)=CC=C%12C(SC=N%13)=C%13C)C)=O)=O)=C%10)CC9)=NC=C8)C(CC7)C6)=C(N)N=N5)C=C3)=O
Biological Activity: L1-CIDE-BRM1-13 (Compound 15) is a linker-drug precursor moiety formed by the covalent conjugation of a PROTAC degrader with a linker for degrader-antibody conjugates (DACs). L1-CIDE-BRM1-13 can be used for the synthesis of DACs[1].
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L1-CIDE-BRM1-13 | L1-CIDE-BRM1-13 (Compound 15) is a linker-drug precursor moiety formed by the covalent conjugation of a PROTAC degrader with a linker for degrader-antibody conjugates (DACs). L1-CIDE-BRM1-13 can be used for the synthesis of DACs. | |||||||||||||||||||||
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Keywords
