Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
Kif2a
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "Kif2a" in MCE Product Catalog:
Referencia número: HY-173522
Target:
Áreas de investigación:
KIF2C-IN-1 is a cell-penetrating, selective KIF2C inhibitor with fluorescent properties (Ex/Em = 410/510 nm). KIF2C-IN-1 exhibits notable cytotoxicity and weak inhibitory effects on KIF2A/B. KIF2C-IN-1 prohibits the dissociation of KIF2C from microtubules. KIF2C-IN-1 inhibiting KIF2C reverses cross-resistance to microtubule-targeting agents. KIF2C-IN-1 reduces tumorigenesis in chemoresistant triple-negative breast cancer (TNBC) model in mice with the combination of Paclitaxel (HY-B0015) .
Referencia número: HY-RS07282
Target:
Áreas de investigación:
KIF2A Human Pre-designed siRNA Set A contains three designed siRNAs for KIF2A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-RS20433
Target:
Áreas de investigación:
Kif2a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Kif2a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-RS26942
Target:
Áreas de investigación:
Kif2a Rat Pre-designed siRNA Set A contains three designed siRNAs for Kif2a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-177898
No. CAS: 1620225-37-7
DHTP is a kinesin-13 family of microtubule depolymerases selective allosteric inhibitor that inhibits kinesin-13 ATPase activity and microtubule depolymerization activity. DHTP inhibits Kif2a and MCAK with IC50 values of 1.2 μM and 4.6 μM, respectively, and does not inhibit other kinesin families. DHTP modulates microtubule dynamics in cells, leading to less dynamic microtubules. DHTP links kinesin-13 overexpression to cancer and Paclitaxel (HY-B0015) resistance. DHTP can be used for the research of cancer .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
