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Results for "

L 735524

" in MedChemExpress (MCE) Product Catalog:

6

阻害剤およびアゴニスト

2

同位体標識化合物

製品番号 製品名 Target 研究分野 構造式
  • HY-B0689
    Indinavir
    Maximum Cited Publications
    8 Publications Verification

    MK-639 free base; L-735524 free base

    		 HIV HIV Protease Apoptosis MMP SARS-CoV Inflammation/Immunology Cancer
    Indinavir (MK-639 free base) is an orally active and selective HIV-1 protease inhibitor with a Ki of 0.54 nM for PR. Indinavir exhibits anticancer activity by inhibiting the activation of MMPs-2 hydrolysis, anti-angiogenesis and inducing apoptosis. Indinavir is also a SARS-CoV 3CL pro inhibitor .
    Indinavir
  • HY-B0689A
    Indinavir sulfate
    Maximum Cited Publications
    8 Publications Verification

    MK-639; L735524

    		 HIV HIV Protease SARS-CoV Apoptosis MMP Infection Cancer
    Indinavir sulfate (MK-639) is an orally active and selective HIV-1 protease inhibitor with a Ki of 0.54 nM for PR. Indinavir sulfate exhibits anticancer activity by inhibiting the activation of MMPs-2 hydrolysis, anti-angiogenesis and inducing apoptosis. Indinavir sulfate is also a SARS-CoV 3CL pro inhibitor .
    Indinavir sulfate
  • HY-B0689B
    Indinavir sulfate ethanolate

    MK-639 ethanolate; L735524 ethanolate

    		 Apoptosis MMP HIV HIV Protease SARS-CoV Infection Cancer
    Indinavir sulfate ethanolate (MK-639 ethanolate) is an orally active and selective HIV-1 protease inhibitor with a Ki of 0.54 nM for PR. Indinavir sulfate ethanolate exhibits anticancer activity by inhibiting the activation of MMPs-2 hydrolysis, anti-angiogenesis and inducing apoptosis. Indinavir sulfate ethanolate is also a SARS-CoV 3CL pro inhibitor .
    Indinavir sulfate ethanolate
  • HY-B0689S
    Indinavir-d6

    MK-639-d6 free base; L-735524-d6 free base

    		 Isotope-Labeled Compounds HIV HIV Protease Inflammation/Immunology
    Indinavir-d6 is the deuterium labeled Indinavir. Indinavir (MK-639; L735524) is a potent and specific HIV protease inhibitor that appears to have good oral bioavailability.
    Indinavir-d6
  • HY-B0689S1
    Indinavir-13C4,15N

    MK-639 free base-13C4,15N; L-735524 free base-13C4,15N

    		 Isotope-Labeled Compounds Apoptosis MMP HIV SARS-CoV HIV Protease Inflammation/Immunology Cancer
    Indinavir- 13C4, 15N (MK-639 (free base)- 13C4, 15N) is 13C and 15N labeled Indinavir. Indinavir (MK-639 free base) is an orally active and selective HIV-1 protease inhibitor with a Ki of 0.54 nM for PR. Indinavir exhibits anticancer activity by inhibiting the activation of MMPs-2 hydrolysis, anti-angiogenesis and inducing apoptosis. Indinavir is also a SARS-CoV 3CL pro inhibitor .
    Indinavir-13C4,15N
  • HY-B0689C
    (threo)-Indinavir

    (threo)-MK-639; (threo)-L735524

    		 HIV Infection
    (Threo)-Indinavir is a protease inhibitor that plays an important role in HIV/AIDS suppression. (Threo)-Indinavir is used as a component of highly active antiretroviral suppression. By inhibiting the viral protease, (threo)-Indinavir ((threo)-MK-639) is able to effectively block the replication of the HIV virus .
    (threo)-Indinavir

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