1 Result for "

LJI308

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "LJI308" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-19713
CAS No.: 1627709-94-7
Research Areas:  

Cancer

LJI308 is a potent pan-ribosomal S6 kinase (RSK) inhibitor, with IC50s of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively. LJI308 inhibits the phosphorylation of RSK (T359/S363) and YB-1 (S102) after irradiation, treatment with EGF, and in cells expressing a KRAS mutation .
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