2 Results for "

LTβR

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "LTβR" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P99459
CAS No.: 909110-25-4
Synonyms: BG 9924; TT-47

Target:  

TNF Receptor CXCR

Research Areas:  

Inflammation/Immunology

Baminercept (BG 9924; TT-47) is an Ig fusion protein targeting the lymphotoxin β receptor (LTβR). Baminercept effectively regulates subsets of circulating immune cells by inhibiting LIGHT, LT-α1β2 and their receptors. Baminercept also increases blood lymphocyte counts and reduces plasma CXCL13 levels. Baminercept carries a high risk of hepatotoxicity. Baminercept can be used in research on rheumatoid arthritis and primary Sjögren's syndrome .
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Cat. No.: HY-123984
CAS No.: 2189366-77-4
Purity:  99.79%
Target:  

NF-κB

Research Areas:  

Metabolic Disease

LTβR-IN-1 (Compound 919278) is a potent, selective lymphotoxin β receptor (LTβR) inhibitor. LTβR-IN-1 also selectively inhibits the nuclear translocation of p52 depended on TNF12A, instead of the nuclear translocation of p65 mediated by TNF-α receptor. LTβR-IN-1 regulates the NF-kB signaling pathway IN a ligand-independent manner .
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