2189366-77-4
Chemical Structure
LTβR-IN-1
- CAS No.: 2189366-77-4
- Formula:C18H16N4O2
- Molecular Weight:320.35
IUPAC Name: (R)-N-(1H-benzo[d]imidazol-2-yl)-2-(1-oxoisoindolin-2-yl)propanamide
InChIKey: PWSSISUOJZBZFT-LLVKDONJSA-N
SMILES: C[C@@H](N(CC1=C2C=CC=C1)C2=O)C(NC3=NC4=CC=CC=C4N3)=O
Biological Activity: LTβR-IN-1 (Compound 919278) is a potent, selective lymphotoxin β receptor (LTβR) inhibitor. LTβR-IN-1 also selectively inhibits the nuclear translocation of p52 depended on TNF12A, instead of the nuclear translocation of p65 mediated by TNF-α receptor. LTβR-IN-1 regulates the NF-kB signaling pathway IN a ligand-independent manner[1].
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LTβR-IN-1 | 99.79% | LTβR-IN-1 (Compound 919278) is a potent, selective lymphotoxin β receptor (LTβR) inhibitor. LTβR-IN-1 also selectively inhibits the nuclear translocation of p52 depended on TNF12A, instead of the nuclear translocation of p65 mediated by TNF-α receptor. LTβR-IN-1 regulates the NF-kB signaling pathway IN a ligand-independent manner. | ||||||||||||||||||||
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Keywords
