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Lantibiotic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Payload (1) Antibiotic (3) Bacterial (3) Drug Derivative (1)
By Research Areas:	Infection (4) Inflammation/Immunology (1)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-106302

Duramycin Moli1901; Lancovutide	Bacterial	Infection Inflammation/Immunology
Duramycin (Moli1901) is a lantibiotic derived from Streptomyces cinnamoneuma. Duramycin also is a antimicrobial peptide. Duramycin can be used for the research of cystic fibrosis (CF) .

HY-P5746

Suicin 65	ADC Payload Antibiotic	Others
Suicin 65 is a class I type B lantibiotic produced by Streptococcus suis. Suicin 65 is active against all S. suis isolates .

HY-N5203

Ala0-Actagardine	Antibiotic Bacterial	Infection
Ala0-Actagardine is a lantibiotic found in the cultures of Actinoplanes liguriae ATCC 31048 .

HY-P2331

Actagardin Antibiotic A 3802-IV-3; Gardimycin	Antibiotic	Infection
Actagardin is a tetracyclic lantibiotic produced by several species of Actinoplanes. It is composed of macrocyclic rings formed by thioether bridges. Actagardin preferably targets Gram-positive bacteria, inhibiting the synthesis of peptidoglycan.

HY-131476

NAI-802	Bacterial	Infection
NAI-802 is a new *lantibiotic. NAI-802 can be produced by Actinoplanes* sp. NAI-802 shows a significant activity against Gram-positive anaerobic bacteria, such as Clostridium difficile, C. butyricum, C. perfringens and Peptostreptococcus asaccharolyticus with MIC ranges of 0.25-2 μg/mL .

HY-165221

1-Dodecanoyl-sn-glycerophosphoethanolamine	Drug Derivative	Others
1-Dodecanoyl-sn-glycerophosphoethanolamine, a derivative of phosphatidylethanolamine, interacts with Cinnamycin (HY-P1695) to induce conformational changes. 1-Dodecanoyl-sn-glycerophosphoethanolamine is applicable to studies related to antibiotic synthesis .

Cat. No.	Product Name	Target	Research Area

HY-P5746

Suicin 65	ADC Payload Antibiotic	Others
Suicin 65 is a class I type B lantibiotic produced by Streptococcus suis. Suicin 65 is active against all S. suis isolates .

HY-P2331

Actagardin Antibiotic A 3802-IV-3; Gardimycin	Antibiotic	Infection
Actagardin is a tetracyclic lantibiotic produced by several species of Actinoplanes. It is composed of macrocyclic rings formed by thioether bridges. Actagardin preferably targets Gram-positive bacteria, inhibiting the synthesis of peptidoglycan.

Duramycin Moli1901; Lancovutide	Microorganisms Classification of Application Fields Inflammation/Immunology Disease Research Fields Source Classification	Bacterial
Duramycin (Moli1901) is a lantibiotic derived from Streptomyces cinnamoneuma. Duramycin also is a antimicrobial peptide. Duramycin can be used for the research of cystic fibrosis (CF) .

Ala0-Actagardine	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial
Ala0-Actagardine is a lantibiotic found in the cultures of Actinoplanes liguriae ATCC 31048 .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Lantibiotic

Inhibitors & Agonists

Peptides

NaturalProducts

Natural
Products