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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
M21 cells
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "M21 cells" in MCE Product Catalog:
Cat. No.: HY-N11644
CAS No.: 111372-80-6
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Cat. No.: HY-187120
CAS No.: 1422528-30-0
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PAIB-SOs-12 is a CYP1A1-activated antimitotic prodrug with affinity for human CYP1A1, with a Ki value of 1.2 μM. PAIB-SOs-12 exhibits nanomolar antiproliferative activity in cancer cells expressing CYP1A1, with a selectivity ratio of over 100 against cancer cells that do not express CYP1A1. PAIB-SOs-12 undergoes CYP1A1-mediated N-dealkylation to form the active metabolite PIB-SO, which induces G2/M cell cycle arrest and microtubule disruption, and shows significantly improved stability in rodent liver microsomes compared to its n-butyl analog. PAIB-SOs-12 can be used in breast cancer-related research .
Cat. No.: HY-184827
CAS No.: 871544-55-7
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1-(2-Chloroacetyl)-3-(2,3-dimethylphenyl) urea is an anticancer agent. 1-(2-Chloroacetyl)-3-(2,3-dimethylphenyl) urea inhibits the growth of colon cancer, cutaneous melanoma and breast cancer. 1-(2-Chloroacetyl)-3-(2,3-dimethylphenyl) urea can be used in the research of colon cancer, cutaneous melanoma and breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
