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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
MAPK15
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "MAPK15" in MCE Product Catalog:
2
2 Cited Publications
CK2/ERK8-IN-1 is a dual casein kinase 2 (CK2) (Ki of 0.25 µM) and ERK8 (MAPK15, ERK7) inhibitor with IC50s of 0.50 μM. CK2/ERK8-IN-1 also binds to PIM1, HIPK2 (homeodomain-interacting protein kinase 2), and DYRK1A with Kis of 8.65 µM, 15.25 µM, and 11.9 µM, respectively. CK2/ERK8-IN-1 has pro-apoptotic efficacy .
Cat. No.: HY-RS08110
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MAPK15 Human Pre-designed siRNA Set A contains three designed siRNAs for MAPK15 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08111
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Mapk15 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mapk15 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08112
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Mapk15 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mapk15 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P702934
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: MAPK15; MAPK 15; Mitogen-Activated Protein Kinase 15; ERK-7; ERK8; ERK-8; ERK7; Extracellular Signal Regulated Kinase 8; Extracellular Signal-Regulated Kinase 7; Extracellular Regulated Kinase 8 Delta; Extracellular Signal-Regulated Kinase 8; Mitogen-Acti
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Cat. No.: HY-P86863
Synonyms: ERK 7 antibody; ERK 8 antibody; ERK-7 antibody; ERK-8 antibody; ERK7 antibody; ERK8 antibody; Extracellular regulated kinase 8 delta antibody; Extracellular signal regulated kinase 8 antibody; Extracellular signal-regulated kinase 7 antibody; Extracellular signal-regulated kinase 8 antibody; ERK 7 antibody; ERK 8 antibody; ERK-7 antibody; ERK-8 antibody; ERK7 antibody; ERK8 antibody; Extracellular regulated kinase 8 delta antibody; Extracellular signal regulated kinase 8 antibody; Extracellular signal-regulated kinase 7 antibody; Extracellular signal-regulated kinase 8 antibody; MAP kinase 15 antibody; MAPK 15 antibody; MAPK15 antibody; Mitogen activated protein kinase 15 antibody; Mitogen-activated protein kinase 15 antibody; MK15_HUMAN antibody;
Cat. No.: HY-180355
CAS No.: 2365230-48-2
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SY-5102 is a potent, selective, and orally active cyclin-dependent kinase (CDK7) inhibitor with a Kd value of 0.03 nM. SY-5102 occupies the ATP-binding pocket of CDK7 via non-covalent binding to inhibit CDK7 activity, and downregulates its phosphorylation of cyclin CDK and RNA polymerase II. SY-5102 inhibits cancer cell proliferation, and induces tumor growth inhibition and regression. SY-5102 can be used in research related to triple-negative breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
