1 Result for "

MC2590

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MC2590" in MCE Product Catalog:

1
1 Cited Publications
Art. -Nr.: HY-152226
CAS. Nr.: 2284460-01-9
Reinheit:  98.71%
Target:  

HDAC Apoptosis

Forschungsgebiete:  

Cancer

MC2590 is a potent pyridine-containing histone deacetylase (HDAC) inhibitor. MC2590 is a inhibitor of HDAC1-3, -6, -8, and -10 (class I/IIb-selective inhibitor) with IC50s of 0.015 μM-0.156 μM. MC2590 also inhibits HDAC isoforms HDAC4, HDAC5, HDAC7, HDAC9, HDAC11 with IC50s of 1.35 μM-3.98 μM. MC2625 induces G2/M cell cycle arrest and modulates pro- and anti-apoptotic microRNAs towards apoptosis induction .
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