2284460-01-9
Chemical Structure
MC2590
- CAS No.: 2284460-01-9
- Formula:C20H17N3O3
- Molecular Weight:347.37
IUPAC Name: (E)-N-hydroxy-3-(5-(2-(naphthalen-1-yl)acetamido)pyridin-2-yl)acrylamide
InChIKey: DTNVLAIWDVXDJR-ZHACJKMWSA-N
SMILES: O=C(NO)/C=C/C1=NC=C(C=C1)NC(CC2=C3C=CC=CC3=CC=C2)=O
Biological Activity: MC2590 is a potent pyridine-containing histone deacetylase (HDAC) inhibitor. MC2590 is a inhibitor of HDAC1-3, -6, -8, and -10 (class I/IIb-selective inhibitor) with IC50s of 0.015 μM-0.156 μM. MC2590 also inhibits HDAC isoforms HDAC4, HDAC5, HDAC7, HDAC9, HDAC11 with IC50s of 1.35 μM-3.98 μM. MC2625 induces G2/M cell cycle arrest and modulates pro- and anti-apoptotic microRNAs towards apoptosis induction[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MC2590 | 98.71% | MC2590 is a potent pyridine-containing histone deacetylase (HDAC) inhibitor. MC2590 is a inhibitor of HDAC1-3, -6, -8, and -10 (class I/IIb-selective inhibitor) with IC50s of 0.015 μM-0.156 μM. MC2590 also inhibits HDAC isoforms HDAC4, HDAC5, HDAC7, HDAC9, HDAC11 with IC50s of 1.35 μM-3.98 μM. MC2625 induces G2/M cell cycle arrest and modulates pro- and anti-apoptotic microRNAs towards apoptosis induction. | ||||||||||||||||||||
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Keywords
