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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
MDCK II cells
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "MDCK II cells" in MCE Product Catalog:
Cat. No.: HY-P991446
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Cat. No.: HY-P12128
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SYN1753 is a selective inhibitor of human neonatal Fc receptor (hFcRn) with a Kd value of 0.5 μM. SYN1753 binds to the albumin-binding site of hFcRn, inhibits the hFcRn-albumin interaction, and thereby suppresses FcRn-mediated transcytosis of human albumin. SYN1753 can be used in studies related to acetaminophen-induced liver injury .
Cat. No.: HY-187428
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LMed 99 is an antiviral agent. LMed 99 inhibits viral RNA synthesis and reduces viral protein expression in a time-dependent manner. LMed 99 potently inhibits Influenza A virus replication. LMed 99 can be used in the research of Influenza A virus infections (H1N1, H5N1) .
Cat. No.: HY-187427
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LMed 93 is an antiviral agent. LMed 93 inhibits the activity of influenza A virus RNA polymerase. LMed 93 suppresses viral RNA synthesis. LMed 93 inhibits the replication of influenza A viruses H5N1 and H1N1. LMed 93 can be used for the research of influenza A virus infections (H1N1, H5N1) .
Cat. No.: HY-16342
CAS No.: 827034-92-4
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NA808 is an Serine Palmitoyltransferase (SPT) inhibitor. NA808 reduces sphingomyelin synthesis, inhibits its activation in hepatic stellate cells, and decreases the expression of α-SMA protein and mRNA, as well as collagen 1A1 mRNA (IC50 0.16, 0.12, and 0.11 μM, respectively). NA808 inhibits HCV replication and reduces NS3 and RdRp protein expression in HCV replicon cells without significant cytotoxicity and exhibits almost no immunosuppressive effect at effective concentrations. NA808 demonstrates broad-spectrum antiviral activity in humanized chimeric liver mice infected with various HCV genotypes, and dose-dependently reduces serum and hepatic HCV RNA levels. NA808 can be used for research on non-alcoholic steatohepatitis and hepatitis C virus infection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
