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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
MDM1
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "MDM1" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-15997
CAS No.: 114528-79-9
Synonyms: (-)-Trans-(1S,2S)-U-50488 hydrochloride
Target:
(-)-U-50488 hydrochloride ((-)-Trans-(1S,2S)-U-50488 hydrochloride) is a selective kappa-opioid receptor (KOR) agonist (Kd=2.2 nM) over μ-opioid receptor (MOR) (Kd=430 nM). (-)-U-50488 hydrochloride is a more active enantiomer than (+) trans-(1R,2R) U-50488 (HY-15997A) or the (±) trans-racemic mixture U-50488 (HY-15997B). (-)-U-50488 hydrochloride has a potent and sustained anti-HIV effect in fected blood monocyte-derived macrophages (MDM) .
Cat. No.: HY-RS18772
Target:
Research Areas:
Mdm1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mdm1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08263
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Research Areas:
MDM1 Human Pre-designed siRNA Set A contains three designed siRNAs for MDM1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25260
Target:
Research Areas:
Mdm1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mdm1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Target:
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ALR-6 is an antagonist of the 5-lipoxygenase (5-LOX) activating protein FLAP and has anti-inflammatory activity. ALR-6 potently inhibits 5-LOX product formation (>80%) in pro-inflammatory M1-MDM and has no significant effect on direct inhibition of 5-LOX [1].
Cat. No.: HY-155408
CAS No.: 903639-13-4
Target:
Research Areas:
ALR-27 is an antagonist of the 5-lipoxygenase (5-LOX) activating protein FLAP and has anti-inflammatory activity. ALR-27 potently inhibits 5-LOX product formation (>80%) in pro-inflammatory M1-MDM, with no significant direct inhibition of 5-LOX. ALR-27 not only reduces prostaglandin and leukotriene (LT) production in neutrophils but also increases the production of specialized prolytic mediators in specific human macrophage phenotypes [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
