114528-79-9

(-)-U-50488 hydrochloride Chemical Structure
114528-79-9

Chemical Structure

(-)-U-50488 hydrochloride

Synonym(s): (-)-Trans-(1S,2S)-U-50488 hydrochloride

  • CAS No.: 114528-79-9
  • Formula:C19H27Cl3N2O
  • Molecular Weight:405.79

IUPAC Name: 2-(3,4-dichlorophenyl)-N-methyl-N-((1S,2S)-2-(pyrrolidin-1-yl)cyclohexyl)acetamide hydrochloride

InChIKey: KGMMGVIYOHGOKQ-APTPAJQOSA-N

SMILES: O=C(N(C)[C@@H]1[C@@H](N2CCCC2)CCCC1)CC3=CC=C(Cl)C(Cl)=C3.[H]Cl

Biological Activity: (-)-U-50488 hydrochloride ((-)-Trans-(1S,2S)-U-50488 hydrochloride) is a selective kappa-opioid receptor (KOR) agonist (Kd=2.2 nM) over μ-opioid receptor (MOR) (Kd=430 nM). (-)-U-50488 hydrochloride is a more active enantiomer than (+) trans-(1R,2R) U-50488 (HY-15997A) or the (±) trans-racemic mixture U-50488 (HY-15997B). (-)-U-50488 hydrochloride has a potent and sustained anti-HIV effect in fected blood monocyte-derived macrophages (MDM)[1].

Cat. No. Product Name Purity Description Pricing
HY-15997 		(-)-U-50488 hydrochloride 98.95% (-)-U-50488 hydrochloride ((-)-Trans-(1S,2S)-U-50488 hydrochloride) is a selective kappa-opioid receptor (KOR) agonist (Kd=2.2 nM) over μ-opioid receptor (MOR) (Kd=430 nM). (-)-U-50488 hydrochloride is a more active enantiomer than (+) trans-(1R,2R) U-50488 (HY-15997A) or the (±) trans-racemic mixture U-50488 (HY-15997B). (-)-U-50488 hydrochloride has a potent and sustained anti-HIV effect in fected blood monocyte-derived macrophages (MDM).
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

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