1. GPCR/G Protein Neuronal Signaling
  2. Opioid Receptor
  3. (±)-U-50488

(±)-U-50488  (Synonyms: (±)-trans-(1R,2R)-U-50488)

Cat. No.: HY-130696A
Handling Instructions Technical Support

(±)-U-50488 ((±)-trans-(1R,2R)-U-50488) is a selective kappa opioid receptor agonist. (±)-U-50488 can improve symptoms related to status epilepticus, but has no significant effect on spontaneous seizure episodes. (±)-U-50488 can be used for research of epilepsy.

For research use only. We do not sell to patients.

(±)-U-50488

(±)-U-50488 Chemical Structure

CAS No. : 67198-13-4

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Description

(±)-U-50488 ((±)-trans-(1R,2R)-U-50488) is a selective kappa opioid receptor agonist. (±)-U-50488 can improve symptoms related to status epilepticus, but has no significant effect on spontaneous seizure episodes. (±)-U-50488 can be used for research of epilepsy[1].

IC50 & Target[1]

κ Opioid Receptor/KOR

 

Molecular Weight

369.33

Formula

C19H26Cl2N2O

CAS No.
SMILES

ClC(C=C1CC(N([C@H]2[C@H](N3CCCC3)CCCC2)C)=O)=C(C=C1)Cl

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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(±)-U-50488
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