BRL 52537 hydrochloride
Based on 1 Customer Validation
BRL 52537 hydrochloride is a highly selective κ-Opioid receptor (KOR) agonist with Kis of 0.24 nM and 1560 nM for κ and μ subtypes, respectively. BRL 52537 hydrochloride decreases ischemia-evoked NO production as a potential mechanism of neuroprotection. BRL 52537 hydrochloride attenuates early stroke damage.
For research use only. We do not sell to patients.
- Purity: 98.14%
- CAS No.: 112282-24-3
- Formula: C18H25Cl3N2O
- Molecular Weight:391.76
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Ki: 0.24 nM (κ-Opioid receptor) and 1560 nM (μ-Opioid receptor)[1]
Chemical Information
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CAS No. 112282-24-3
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Appearance Solid
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Molecular Weight 391.76
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Formula C18H25Cl3N2O
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Color Off-white to light yellow
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SMILES
O=C(CC1=CC=C(C(Cl)=C1)Cl)N2CCCCC2CN3CCCC3.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
Methanol : 25 mg/mL (63.81 mM; Need ultrasonic)
DMSO : 5 mg/mL (12.76 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / Methanol | 1 mM | 2.5526 mL | 12.7629 mL | 25.5258 mL | 63.8146 mL |
| 5 mM | 0.5105 mL | 2.5526 mL | 5.1052 mL | 12.7629 mL | |
| 10 mM | 0.2553 mL | 1.2763 mL | 2.5526 mL | 6.3815 mL | |
| Methanol | 15 mM | 0.1702 mL | 0.8509 mL | 1.7017 mL | 4.2543 mL |
| 20 mM | 0.1276 mL | 0.6381 mL | 1.2763 mL | 3.1907 mL | |
| 25 mM | 0.1021 mL | 0.5105 mL | 1.0210 mL | 2.5526 mL | |
| 30 mM | 0.0851 mL | 0.4254 mL | 0.8509 mL | 2.1272 mL | |
| 40 mM | 0.0638 mL | 0.3191 mL | 0.6381 mL | 1.5954 mL | |
| 50 mM | 0.0511 mL | 0.2553 mL | 0.5105 mL | 1.2763 mL | |
| 60 mM | 0.0425 mL | 0.2127 mL | 0.4254 mL | 1.0636 mL |
BRL 52537 hydrochloride Related Classifications
HY-101079 Related Classifications
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