112282-24-3
Chemical Structure
BRL 52537 hydrochloride
- CAS No.: 112282-24-3
- Formula:C18H25Cl3N2O
- Molecular Weight:391.76
IUPAC Name: 2-(3,4-dichlorophenyl)-1-(2-(pyrrolidin-1-ylmethyl)piperidin-1-yl)ethanone hydrochloride
InChIKey: NGVLSOWJSUUYDE-UHFFFAOYSA-N
SMILES: O=C(CC1=CC=C(C(Cl)=C1)Cl)N2CCCCC2CN3CCCC3.Cl
Biological Activity: BRL 52537 hydrochloride is a highly selective κ-Opioid receptor (KOR) agonist with Kis of 0.24 nM and 1560 nM for κ and μ subtypes, respectively. BRL 52537 hydrochloride decreases ischemia-evoked NO production as a potential mechanism of neuroprotection. BRL 52537 hydrochloride attenuates early stroke damage[1].
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BRL 52537 hydrochloride | 98.14% | BRL 52537 hydrochloride is a highly selective κ-Opioid receptor (KOR) agonist with Kis of 0.24 nM and 1560 nM for κ and μ subtypes, respectively. BRL 52537 hydrochloride decreases ischemia-evoked NO production as a potential mechanism of neuroprotection. BRL 52537 hydrochloride attenuates early stroke damage. | ||||||||||||||||||||
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Keywords
