2 Results for "

MKN-74

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "MKN-74" in MCE Product Catalog:

Cat. No.: HY-P1997
CAS No.: 34787-28-5
Synonyms: Desferrichrome; DFC; N-Desferriferrichrome
Target:  

JNK Apoptosis

Research Areas:  

Infection Cancer

Ferrichrome Iron-free (Desferrichrome; DFC; N-Desferriferrichrome) is the ligand form of iron-loaded Ferrichrome when it is not bound to Fe 3+. Ferrichrome Iron-free induces apoptosis in gastric cancer cells by activating the JNK-DDIT3 apoptotic axis. As an iron chelator, Ferrichrome Iron-free enables dual-modal imaging of HER2 via conjugation with SiR and Trastuzumab (HY-P9907). Ferrichrome Iron-free can be used in the research of gastric cancer and HER2-overexpressing cancers .
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Cat. No.: HY-181578
CAS No.: 3077970-78-3
Target:  

NAMPT Apoptosis

Research Areas:  

Cancer

Nampt-IN-17 is an selective orally active NAMPT inhibitor with a human NAMPT IC50 of 17 nM and Ki of 25.9 nM. Nampt-IN-17 depletes intracellular NAD + and ATP, disrupts mitochondrial membrane potential, suppresses cell proliferation, self-renewal, invasion, and migration, induces cell-cycle arrest and apoptosis. Nampt-IN-17 exhibits selective activity against NAPRT-deficient gastric cancer cells. Nampt-IN-17 can be used for the research of NAPRT-deficient gastric cancer .
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