34787-28-5

Ferrichrome Iron-free Chemical Structure
34787-28-5

Chemical Structure

Ferrichrome Iron-free

Synonym(s): Desferrichrome; DFC; N-Desferriferrichrome

  • CAS No.: 34787-28-5
  • Formula:C27H45N9O12
  • Molecular Weight:687.70

IUPAC Name: N,N',N''-(((2S,5S,8S)-3,6,9,12,15,18-hexaoxo-1,4,7,10,13,16-hexaazacyclooctadecane-2,5,8-triyl)tris(propane-3,1-diyl))tris(N-hydroxyacetamide)

InChIKey: ZFDAUYPBCXMSBF-ACRUOGEOSA-N

SMILES: CC(N(CCC[C@@H](C(N[C@@H](CCCN(C(C)=O)O)C(NCC(NCC(NCC(N[C@H]1CCCN(C(C)=O)O)=O)=O)=O)=O)=O)NC1=O)O)=O

Biological Activity: Ferrichrome Iron-free (Desferrichrome; DFC; N-Desferriferrichrome) is the ligand form of iron-loaded Ferrichrome when it is not bound to Fe3+. Ferrichrome Iron-free induces apoptosis in gastric cancer cells by activating the JNK-DDIT3 apoptotic axis. As an iron chelator, Ferrichrome Iron-free enables dual-modal imaging of HER2 via conjugation with SiR and Trastuzumab (HY-P9907). Ferrichrome Iron-free can be used in the research of gastric cancer and HER2-overexpressing cancers[1][2].

Cat. No. Product Name Purity Description Pricing
HY-P1997 		Ferrichrome Iron-free 98.5% Ferrichrome Iron-free (Desferrichrome; DFC; N-Desferriferrichrome) is the ligand form of iron-loaded Ferrichrome when it is not bound to Fe3+. Ferrichrome Iron-free induces apoptosis in gastric cancer cells by activating the JNK-DDIT3 apoptotic axis. As an iron chelator, Ferrichrome Iron-free enables dual-modal imaging of HER2 via conjugation with SiR and Trastuzumab (HY-P9907). Ferrichrome Iron-free can be used in the research of gastric cancer and HER2-overexpressing cancers.
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