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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
MLLT1/3
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "MLLT1/3" in MCE Product Catalog:
2
2 Cited Publications
Target:
Research Areas:
SGC-iMLLT is a first-in-class chemical probe and a potent, selective inhibitor of MLLT1/3-histone interactions with an IC50 of 0.26 μM. SGC-iMLLT shows high binding activity towards MLLT1 YEATS domain (YD) and MLLT3 YD (AF9/YEATS3) with Kds of 0.129 and 0.077 μM, respectively [1].
Cat. No.: HY-176821
CAS No.: 2650530-01-9
Target:
Research Areas:
PFI-6N is a negative control compound of PFI-6 (HY-155412). PFI-6N is completely inactive against YEATS domain (MLLT1/3 and YEATS2/4) by methylating the amide of PFI-6 [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
