1 Result for "

MRK898

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MRK898" in MCE Product Catalog:

Cat. No.: HY-153584
CAS No.: 461450-30-6
Purity:  99.48%
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

MRK-898 is an orally active GABA(A) receptor modulator. MRK-898 binds to α1, α2, α3 or α5 subunit of GABA(A) receptor with Ki values of 1.2 nM, 1.0 nM, 0.73 nM, and 0.50 nM, respectively. However, α1-containing GABA(A) receptors are identified as the "sedative" and α2- and/or α3-containing receptors as the "anxiolytic" subtype(s) .
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