1 Result for "

MTL-005

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "MTL-005" in MCE Product Catalog:

Cat. No.: HY-19938
CAS No.: 1030303-53-7
Research Areas:  

Cancer

MTL-005 is a boron-containing radiosensitizer used in Boron Neutron Capture Therapy (BNCT). MTL-005 enriches the boron-10 isotope in tumor tissues, causing nuclear fission under thermal neutron irradiation, releasing high linear energy transfer (LET) α particles and lithium ions, which selectively destroy tumor cells while minimizing damage to surrounding normal tissues. MTL-005 significantly controlls the tumor progression in the SCCVII squamous cell carcinoma mouse model and prolonged the survival of the mice. MTL-005 can be used to study solid tumors such as head and neck cancer.
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