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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
Milnacipran
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "Milnacipran" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-B0168
CAS No.: 92623-85-3
Target:
Research Areas:
Milnacipran is an orally active Serotonin (HY-B1473A) and Norepinephrine (HY-13715) reuptake inhibitor. Milnacipran inhibits monoamine transporters, especially the norepinephrine transporter and the serotonin transporter (Ki values of 31 and 8.5 nM, respectively). Milnacipran inhibits pERK1/2 activation. Milnacipran has antidepressant, anxiolytic and analgesic properties. Milnacipran inhibits biting behavior in mice. Milnacipran can be used in the study of major depressive disorder, anxiety disorders, and neuropathic pain (e.g., fibromyalgia) .
2
2 Cited Publications
Cat. No.: HY-B0168A
CAS No.: 101152-94-7
Target:
Research Areas:
Milnacipran hydrochloride is an orally active Serotonin (HY-B1473A) and Norepinephrine (HY-13715) reuptake inhibitor. Milnacipran hydrochloride inhibits monoamine transporters, especially the norepinephrine transporter and the serotonin transporter (Ki values of 31 and 8.5 nM, respectively). Milnacipran hydrochloride inhibits pERK1/2 activation. Milnacipran hydrochloride has antidepressant, anxiolytic and analgesic properties. Milnacipran hydrochloride inhibits biting behavior in mice. Milnacipran hydrochloride can be used in the study of major depressive disorder, anxiety disorders, and neuropathic pain (e.g., fibromyalgia) .
1
1 Cited Publications
Cat. No.: HY-B0168B
CAS No.: 175131-60-9
Synonyms: (1S,2R)-Milnacipran hydrochloride; F-2695 hydrochloride
Research Areas:
Levomilnacipran ((1S,2R)-Milnacipran) hydrochloride is the enantiomer of Milnacipran (HY-B0168) and a strong substrate of P-gp that can cross the blood-brain barrier. Levomilnacipran hydrochloride is a serotonin and norepinephrine reuptake inhibitor, with IC50 values of 10.5 nM and 19.0 nM, and Ki values of 92.2 nM and 1.2 nM for human norepinephrine transporter (NET) and serotonin transporter (SERT), respectively. Levomilnacipran hydrochloride has antidepressant and anxiolytic activities. Levomilnacipran hydrochloride can be used for the research of depression .
Synonyms: (1R,2S)-Milnacipran; F2696
Research Areas:
Dextromilnacipran ((1R,2S)-Milnacipran; F2696) is an orally active Serotonin (HY-B1473A)/Noradrenaline (HY-13715) transporter inhibitor. Dextromilnacipran inhibits Serotonin and Noradrenaline reuptake. Dextromilnacipran can be used for the research of depression, fibromyalgia .
Cat. No.: HY-B0168S
CAS No.: 1217774-40-7
Cat. No.: HY-14794A
CAS No.: 96847-54-0
Synonyms: (1S,2R)-Milnacipran; F2695
Research Areas:
Levomilnacipran ((1S,2R)-Milnacipran) is the enantiomer of Milnacipran (HY-B0168) and a strong substrate of P-gp that can cross the blood-brain barrier. Levomilnacipran is a serotonin and norepinephrine reuptake inhibitor, with IC50 values of 10.5 nM and 19.0 nM, and Ki values of 92.2 nM and 1.2 nM for human norepinephrine transporter (NET) and serotonin transporter (SERT), respectively. Levomilnacipran has antidepressant and anxiolytic activities. Levomilnacipran hydrochloride can be used for the research of depression .
Cat. No.: HY-14794S
CAS No.: 1127352-73-1
Synonyms: (1R,2S)-Milnacipran-d6; F2696-d6
Cat. No.: HY-B0168AR
CAS No.: 101152-94-7
Research Areas:
Milnacipran (hydrochloride) (Standard) is the analytical standard of Milnacipran hydrochloride (HY-B0168A). This product is intended for research and analytical applications. Milnacipran hydrochloride is an orally active Serotonin (HY-B1473A) and Norepinephrine (HY-13715) reuptake inhibitor. Milnacipran hydrochloride inhibits monoamine transporters, especially the norepinephrine transporter and the serotonin transporter (Ki values of 31 and 8.5 nM, respectively). Milnacipran hydrochloride inhibits pERK1/2 activation. Milnacipran hydrochloride has antidepressant, anxiolytic and analgesic properties. Milnacipran hydrochloride inhibits biting behavior in mice. Milnacipran hydrochloride can be used in the study of major depressive disorder, anxiety disorders, and neuropathic pain (e.g., fibromyalgia) .
Cat. No.: HY-B0168AS
CAS No.: 2750534-79-1
Cat. No.: HY-B0168BS
Synonyms: (1S,2R)-Milnacipran-d5 hydrochloride; F-2695-d5 hydrochloride
Cat. No.: HY-14794AS
CAS No.: 2747914-23-2
Synonyms: (1S,2R)-Milnacipran-d10 hydrochloride; F2695-d10 hydrochloride
Cat. No.: HY-14794B
CAS No.: 175131-61-0
Synonyms: (1R,2S)-Milnacipran hydrochloride; F2696 hydrochloride
Research Areas:
Dextromilnacipran ((1R,2S)-Milnacipran; F2696) hydrochloride is an orally active Serotonin (HY-B1473A)/Noradrenaline (HY-13715) transporter inhibitor. Dextromilnacipran hydrochloride inhibits Serotonin and Noradrenaline reuptake. Dextromilnacipran hydrochloride can be used for the research of depression, fibromyalgia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
