1. Neuronal Signaling
  2. Serotonin Transporter
  3. Milnacipran ((1S-cis) hydrochloride)

Milnacipran ((1S-cis) hydrochloride)  (Synonyms: Levomilnacipran hydrochloride; F-2695 hydrochloride)

Cat. No.: HY-B0168B Purity: 99.95%
COA Handling Instructions

Milnacipran (1S-cis) hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI), used in the clinical treatment of fibromyalgia.

For research use only. We do not sell to patients.

Milnacipran ((1S-cis) hydrochloride) Chemical Structure

Milnacipran ((1S-cis) hydrochloride) Chemical Structure

CAS No. : 175131-60-9

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in Water
ready for reconstitution
USD 99 In-stock
Solution
10 mM * 1 mL in Water USD 99 In-stock
Solid
5 mg USD 90 In-stock
10 mg USD 135 In-stock
25 mg USD 270 In-stock
50 mg USD 405 In-stock
100 mg USD 607 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other Forms of Milnacipran ((1S-cis) hydrochloride):

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • Customer Review

Description

Milnacipran (1S-cis) hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI), used in the clinical treatment of fibromyalgia.

Clinical Trial
Molecular Weight

282.81

Formula

C15H23ClN2O

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C([C@]1(C2=CC=CC=C2)[C@H](CN)C1)N(CC)CC.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (176.80 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5359 mL 17.6797 mL 35.3594 mL
5 mM 0.7072 mL 3.5359 mL 7.0719 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (353.59 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.5359 mL 17.6797 mL 35.3594 mL 88.3986 mL
5 mM 0.7072 mL 3.5359 mL 7.0719 mL 17.6797 mL
10 mM 0.3536 mL 1.7680 mL 3.5359 mL 8.8399 mL
15 mM 0.2357 mL 1.1786 mL 2.3573 mL 5.8932 mL
20 mM 0.1768 mL 0.8840 mL 1.7680 mL 4.4199 mL
25 mM 0.1414 mL 0.7072 mL 1.4144 mL 3.5359 mL
30 mM 0.1179 mL 0.5893 mL 1.1786 mL 2.9466 mL
40 mM 0.0884 mL 0.4420 mL 0.8840 mL 2.2100 mL
50 mM 0.0707 mL 0.3536 mL 0.7072 mL 1.7680 mL
60 mM 0.0589 mL 0.2947 mL 0.5893 mL 1.4733 mL
80 mM 0.0442 mL 0.2210 mL 0.4420 mL 1.1050 mL
100 mM 0.0354 mL 0.1768 mL 0.3536 mL 0.8840 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Milnacipran ((1S-cis) hydrochloride) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Milnacipran ((1S-cis) hydrochloride)
Cat. No.:
HY-B0168B
Quantity:
MCE Japan Authorized Agent: