2 Results for "

N0886

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "N0886" in MCE Product Catalog:

3
Aloin B
Aloin B
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3 Cited Publications
Cat. No.: HY-N0886
CAS No.: 28371-16-6
Synonyms: Isobarbaloin
Category:  

Quinones Liliaceae Anthraquinones Other Diseases Aloe vera (L.) Burm. f. Phenols Polyphenols Plants Disease Research Fields

Target:  

SARS-CoV Virus Protease

Aloin B (Isobarbaloin) is an orally active SARS-CoV-2 papain-like protease (PLpro) inhibitor with an IC50 of 16.08 μM (hydrolytic activity) and 17.51 μM (deubiquitinase activity). Aloin B is metabolized by rat intestinal flora into aloe-emodin-9-anthrone to exert laxative effects. Aloin B inhibits TPA (HY-18739)-induced ear edema, putrescine elevation, and tumor promotion in mouse skin. Aloin B can be used in research related to anti-inflammation, tumor promotion inhibition, coronavirus disease 2019 (COVID-19) and constipation .
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Aloin B (Standard)
Aloin B (Standard)
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Cat. No.: HY-N0886R
CAS No.: 28371-16-6
Synonyms: Isobarbaloin (Standard)
Category:  

Quinones Liliaceae Anthraquinones Aloe vera (L.) Burm. f. Phenols Polyphenols Plants

Target:  

Reference Standards Virus Protease SARS-CoV

Aloin B (Isobarbaloin) (Standard) is the analytical standard of Aloin B. This product is intended for research and analytical applications. Aloin B is an orally active SARS-CoV-2 papain-like protease (PLpro) inhibitor with an IC50 of 16.08 μM (hydrolytic activity) and 17.51 μM (deubiquitinase activity). Aloin B is metabolized by rat intestinal flora into aloe-emodin-9-anthrone to exert laxative effects. Aloin B inhibits TPA (HY-18739)-induced ear edema, putrescine elevation, and tumor promotion in mouse skin. Aloin B can be used in research related to anti-inflammation, tumor promotion inhibition, coronavirus disease 2019 (COVID-19) and constipation .
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