1 Result for "

NA17

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NA17" in MCE Product Catalog:

Cat. No.: HY-169688
CAS No.: 1708948-28-0
Target:  

MDM-2/p53 Apoptosis

Research Areas:  

Cancer

NA-17 is a naphthalimide compound with anti-tumor activity and lower toxicity to normal cells like HL-7702 and WI-38. NA-17 exhibits a p53-dependent selective inhibition in various NSCLC cells, inducing the accumulation of active p53 in the mitochondria and nuclei of NSCLC cells. NA-17 can cause cell cycle arrest in the G1 phase, leading to apoptosis and cell death .
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