1 Result for "

NEPP11

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "NEPP11" in MCE Product Catalog:

Cat. No.: HY-180327
CAS No.: 313051-12-6
NEPP11 is a cyclopentenone prostaglandin analogue. NEPP11 can inhibit glutamate-induced HT22 cell death in mouse hippocampus and prevent manganese-induced apoptosis in PC12 cells. NEPP11 can activate Nrf2 and maintain MEK1/2 and ERK1/2 activity by inhibiting c-Raf downregulation. NEPP11 exerts a neuroprotective effect in a mouse model of focal cerebral ischemia caused by permanent middle cerebral artery occlusion .
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