1 Result for "

NSC-248958

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NSC-248958" in MCE Product Catalog:

Cat. No.: HY-134090
CAS No.: 51867-94-8
Synonyms: Antibiotic TS 885; NSC 248958
Target:  

Bacterial VSV

Research Areas:  

Infection

9-Methylstreptimidone is a microbial metabolite originally isolated from Streptomyces sp. S-885 that has antifungal and antiviral activities. It is active against several fungi, including S. sake, S. fragilis, R. rubra, T. rubra, and C. albidus (MICs=4-20 μg/mL) and has antiviral activity against poliovirus, vesicular stomatitis virus (VSV), and Newcastle disease virus (NDV) in vitro (MIC=0.02 μg/mL for all). 9-Methylstreptimidone increases survival in mouse models of infection with influenza A2 (H2N2) or C. albicans when administered prior to infection.
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