6 Results for "

Oxaprozin

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Oxaprozin" in MCE Product Catalog:

Cat. No.: HY-B0808
CAS No.: 21256-18-8
Synonyms: Oxaprozinum; Wy21743
Target:  

COX NF-κB Akt IKK Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

Oxaprozin is an orally active and potent COX inhibitor, with IC50 values of 2.2 μM for human platelet COX-1 and and 36 μM for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-κB. Oxaprozin induces cell apoptosis. Oxaprozin shows anti-inflammatory activity. Oxaprozin-mediated inhibition of the Akt/IKK/NF-κB pathway contributes to its anti-inflammatory properties .
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Cat. No.: HY-B0808A
CAS No.: 174064-08-5
Synonyms: Oxaprozinum potassium; Wy21743 potassium
Target:  

COX NF-κB Akt IKK Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

Oxaprozin potassium is an orally active and potent COX inhibitor, with IC50 values of 2.2 μM for human platelet COX-1 and and 36 μM for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin potassium also inhibits the activation of NF-κB. Oxaprozin potassium induces cell apoptosis. Oxaprozin potassium shows anti-inflammatory activity. Oxaprozin potassium-mediated inhibition of the Akt/IKK/NF-κB pathway contributes to its anti-inflammatory properties .
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Cat. No.: HY-B0808R
CAS No.: 21256-18-8
Synonyms: Oxaprozinum (Standard); Wy21743 (Standard)
Oxaprozin (Standard) is the analytical standard of Oxaprozin. This product is intended for research and analytical applications. Oxaprozin is an orally active and potent COX inhibitor, with IC50 values of 2.2 μM for human platelet COX-1 and and 36 μM for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-κB. Oxaprozin induces cell apoptosis. Oxaprozin shows anti-inflammatory activity. Oxaprozin-mediated inhibition of the Akt/IKK/NF-κB pathway contributes to its anti-inflammatory properties .
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Cat. No.: HY-B0808S
CAS No.: 2070015-11-9
Synonyms: Wy-21743-d4
Oxaprozin-d4 is the deuterium labeled Oxaprozin, which is a non-steroidal anti-inflammatory agent (NSAID).
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Cat. No.: HY-W709448
Synonyms: Oxaprozinum-d10; Wy21743-d10
Oxaprozin-d10 (Oxaprozinum-d10; Wy21743-d10) is the deuterium labeled Oxaprozin (HY-B0808). Oxaprozin is an orally active and potent COX inhibitor, with IC50 values of 2.2 μM for human platelet COX-1 and and 36 μM for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-κB. Oxaprozin induces cell apoptosis. Oxaprozin shows anti-inflammatory activity. Oxaprozin-mediated inhibition of the Akt/IKK/NF-κB pathway contributes to its anti-inflammatory properties .
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Cat. No.: HY-B0808S1
CAS No.: 2933758-40-6
Synonyms: Oxaprozinum-d5; Wy21743-d5
Oxaprozin-d5 is deuterium labeled Oxaprozin. Oxaprozin is an inhibitor of both COX-1 and COX-2 with IC50s of 2.2 μM and 36 μM for human platelet COX-1 and IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-κB.
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