1 Result for "

PA-082

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PA-082" in MCE Product Catalog:

Cat. No.: HY-180398
CAS No.: 95520-87-9
Target:  

PPAR PGC-1α

Research Areas:  

Metabolic Disease

PA-082 is a selective PPAR-γ modulator that functions as a partial agonist. PA-082 causes partial recruitment of SRC1, TIF2, SRC3 and full recruitment of PGC1-α to PPAR-γ ligand-binding domain. PA-082 prevents triglyceride accumulation during de novo adipogenesis and antagonizes Rosiglitazone (HY-17386)-induced lipid accumulation. PA-082 potentiates insulin-stimulated glucose uptake in adipocytes and protects against TNFα-induced insulin resistance. PA-082 can be used for the research of type 2 diabetes .
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