5 Results for "

PARP9

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "PARP9" in MCE Product Catalog:

  • Targets Recommended:
TFMU-ADPr
TFMU-ADPr
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Cat. No.: HY-146248
CAS No.: 2412923-11-4
TFMU-ADPr is a selective reporter substrate of SARS-CoV-2 Macro1 (IC50=0.59 μM), with an excitation wavelength (λEx) of 385 nm, and an emission wavelength (λEm) of 502 nm (or 495 nm). TFMU-ADPr can also undergo enzymatic hydrolysis with Poly(ADP-ribose) Glycohydrolase (PARG) sourced from human, Tetrahymena thermophila and ADP-ribosylhydrolase 3 from human to release fluorophores, thereby directly reporting total poly (ADP-ribose) hydrolase activity. TFMU-ADPr binds to the ADPr-binding site of SARS-CoV-2 Macro1, and its TFMU moiety inserts into the narrow hydrophobic groove of this protein. TFMU-ADPr can thus be used to evaluate small-molecule inhibitors targeting PAR hydrolases under in vitro conditions, to investigate the regulatory mechanisms of ADP-ribosyl catabolic enzymes, or to detect PAR hydrolase activity in whole-cell lysate assays. TFMU-ADPr is also applicable to COVID-19-related research .
PARP9 Human Pre-designed siRNA Set A
PARP9 Human Pre-designed siRNA Set A
Cat. No.: HY-RS10071
Target:  

Small Interfering RNA (siRNA)

Research Areas:  

Others

PARP9 Human Pre-designed siRNA Set A contains three designed siRNAs for PARP9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Parp9 Rat Pre-designed siRNA Set A
Parp9 Rat Pre-designed siRNA Set A
Cat. No.: HY-RS26577
Target:  

Small Interfering RNA (siRNA)

Research Areas:  

Others

Parp9 Rat Pre-designed siRNA Set A contains three designed siRNAs for Parp9 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Parp9 Mouse Pre-designed siRNA Set A
Parp9 Mouse Pre-designed siRNA Set A
Cat. No.: HY-RS20074
Target:  

Small Interfering RNA (siRNA)

Research Areas:  

Others

Parp9 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Parp9 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

CDK9/PARP-IN-1
CDK9/PARP-IN-1
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Cat. No.: HY-170942
CAS No.: 3032818-67-7
Target:  

CDK PARP

Research Areas:  

Cancer

CDK9/PARP-IN-1 (compound 37) is a CDK9/PARP inhibitor. CDK9/PARP-IN-1 inhibits CDK9 and PARP1 with IC50s of 118 and 107 nM, respectively. CDK9/PARP-IN-1 exhibits broad-spectrum antiproliferative effects across multiple cancer cell lines .
Assay Types