3032818-67-7
3032818-67-7
Chemical Structure
CDK9/PARP-IN-1
- CAS No.: 3032818-67-7
- Formula:C38H34F2N8O3
- Molecular Weight:688.73
SMILES: O=C1NN=C(CC2=CC=C(F)C(C(N3CCN(CC4=CC(NC5=NC=NC(C6=CC=C(F)C=C6OCC)=C5)=NC=C4)CC3)=O)=C2)C7=C1C=CC=C7
Biological Activity: CDK9/PARP-IN-1 (compound 37) is a CDK9/PARP inhibitor. CDK9/PARP-IN-1 inhibits CDK9 and PARP1 with IC50s of 118 and 107 nM, respectively. CDK9/PARP-IN-1 exhibits broad-spectrum antiproliferative effects across multiple cancer cell lines[1].
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CDK9/PARP-IN-1 | CDK9/PARP-IN-1 (compound 37) is a CDK9/PARP inhibitor. CDK9/PARP-IN-1 inhibits CDK9 and PARP1 with IC50s of 118 and 107 nM, respectively. CDK9/PARP-IN-1 exhibits broad-spectrum antiproliferative effects across multiple cancer cell lines. | |||||||||||||||||||||
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References
Keywords
