1 Result for "

PNRI299

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PNRI299" in MCE Product Catalog:

Cat. No.: HY-15131
CAS No.: 550368-41-7
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

PNRI-299 is a selective AP-1 transcription inhibitor with an IC50 of 20 uM. PNRI-299 is a selective APE/Ref-1 inhibitor. PNRI-299 has no effect on NF-κB transcription or thioredoxin (up to 200 uM). PNRI-299 significantly reduces airway eosinophil infiltration, mucus hypersecretion, edema, and IL-4 levels in a mouse asthma model .
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