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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
PNU200577
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "PNU200577" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-76569
CAS No.: 207679-81-0
Synonyms: PNU-200577; 5-Hydroxymethyl Tolterodine
Target:
Research Areas:
Desfesoterodine (PNU-200577) is a potent and selective muscarinic receptor (mAChR) antagonist with a KB and a pA2 of 0.84 nM and 9.14, respectively . Desfesoterodine is a major pharmacologically active metabolite of Tolterodine (PNU-200583; HY-A0024) and Fesoterodine (HY-70053) . Desfesoterodine improves cerebral infarction induced detrusor overactivity in rats .
Cat. No.: HY-76569R
CAS No.: 207679-81-0
Synonyms: PNU-200577 (Standard); 5-Hydroxymethyl Tolterodine (Standard)
Target:
Research Areas:
Desfesoterodine (Standard) is the analytical standard of Desfesoterodine. This product is intended for research and analytical applications. Desfesoterodine (PNU-200577) is a potent and selective muscarinic receptor (mAChR) antagonist with a KB and a pA2 of 0.84 nM and 9.14, respectively . Desfesoterodine is a major pharmacologically active metabolite of Tolterodine (PNU-200583; HY-A0024) and Fesoterodine (HY-70053) . Desfesoterodine improves cerebral infarction induced detrusor overactivity in rats .
Cat. No.: HY-76570
CAS No.: 200801-70-3
Synonyms: (Rac)-Desfesoterodine; (Rac)-PNU-200577
Target:
Research Areas:
(Rac)-5-Hydroxymethyl Tolterodine ((Rac)-Desfesoterodine), an active metabolite of Tolterodine, is a mAChR antagonist (Ki values of 2.3 nM, 2 nM, 2.5 nM, 2.8 nM, and 2.9 nM for M1, M2, M3, M4, and M5 receptors, respectively). (Rac)-5-Hydroxymethyl Tolterodine can be used for overactive bladder research .
Cat. No.: HY-76569B
CAS No.: 380636-49-7
Synonyms: PNU-200577 formic
Target:
Research Areas:
5-Hydroxymethyl tolterodine (formate) (PNU-200577 (formic)) is an active metabolite of the muscarinic acetylcholine receptor antagonists Tolterodine (HY-A0024) and Fesoterodine (HY-70053). 5-Hydroxymethyl tolterodine (formate) is formed from tolterodine by the cytochrome P450 (CYP) isoform CYP2D6 and from fesoterodine by plasma esterases.
Cat. No.: HY-76569S1
CAS No.: 1191280-58-6
Synonyms: PNU-200577-d14; 5-Hydroxymethyl Tolterodine-d14
Cat. No.: HY-76569S
Synonyms: PNU-200577-d5; 5-Hydroxymethyl Tolterodine-d5
Cat. No.: HY-76570S2
CAS No.: 2012598-78-4
Synonyms: (Rac)-Desfesoterodine-d5; (Rac)-PNU-200577-d5
Cat. No.: HY-76570A
CAS No.: 250214-40-5
Synonyms: (Rac)-Desfesoterodine hydrochloride; (Rac)-PNU-200577 hydrochloride
Target:
Research Areas:
(Rac)-5-Hydroxymethyl Tolterodine ((Rac)-Desfesoterodine) hydrochloride, an active metabolite of Tolterodine, is a mAChR antagonist (Ki values of 2.3 nM, 2 nM, 2.5 nM, 2.8 nM, and 2.9 nM for M1, M2, M3, M4, and M5 receptors, respectively). (Rac)-5-Hydroxymethyl Tolterodine hydrochloride can be used for overactive bladder research .
Cat. No.: HY-76570S
CAS No.: 1185071-13-9
Synonyms: (Rac)-Desfesoterodine-d14; (Rac)-PNU-200577-d14
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
