1 Result for "

PZ2891

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PZ2891" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-124634
CAS No.: 2170608-82-7
Purity:  99.68%
Target:  

PANK

Research Areas:  

Neurological Disease

PZ-2891 is an orally bioavailable, brain penetrant pantothenate kinase (PANK) modulator. PZ-2891 act as an orthosteric inhibitor at high concentrations and an allosteric activator at lower sub-saturating concentrations. PZ-2891 inhibits human pantothenate kinases PANK1β, PANK2, and PANK3 with IC50s of 40.2 nM, 0.7 nM and 1.3 nM, respectively .
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