1 Result for "

Panduratin A

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Panduratin A" in MCE Product Catalog:

Panduratin A
Panduratin A
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Cat. No.: HY-N11722
CAS No.: 89837-52-5
Category:  

Boesenbergia rotunda  Phenols Polyphenols Plants Zingiberaceae

Target:  

Apoptosis NF-κB Keap1-Nrf2 AMPK Autophagy SARS-CoV DNA Methyltransferase

Panduratin A is an orally active natural compound with multiple pharmacological activities. By specifically inhibiting the NF-κB signaling pathway, Panduratin A exerts potent anti-inflammatory and antioxidant effects in intestinal and vascular inflammation models. Panduratin A exerts a definite protective effect against Colistin (HY-113678)-induced nephrotoxicity by alleviating oxidative stress, improving mitochondrial dysfunction and inhibiting cell apoptosis. Panduratin A activates autophagy via an AMPK-dependent pathway and exhibits anti-tuberculosis activity. Panduratin A exerts antiviral effects by inhibiting the methyltransferase (DNA Methyltransferase) of SARS-CoV-2 .
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